MULTI-DRUG RESISTANCE (MDR1) GENE AND P-GLYCOPROTEIN INFLUENCE ON PHARMACOKINETIC AND PHARMACODYMANIC OF THERAPEUTIC DRUGS

Multi-drug resistance (MDR1) gene and P-glycoprotein influence on pharmacokinetic and pharmacodymanic of therapeutic drugs

(MDR1) gene expressed in tumor cells and also in several normal tissues, such as intestine, liver, kidney, blood-brain barrier, spinal cord, and placenta.P-gp has been identified in mice, rat, bovine, monkey, rodents, and human beings and has been receiving a particular clinical relevance because this protein expression limits brain access and inte

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A general equilibrium model of trilateral trade with oil duopoly

I study the economic implications of the world oil market dominated by OPEC and non-OPEC major oil producing countries using a general equilibrium model of trilateral trade with oil duopoly.There model are three countries and three goods, x, y, and oil (z).Home (H) is endowed with good x.Foreign (F) is endowed with good y and also produces oil (z).

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